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Filtered Search Results
Medchemexpress LLC Naluzotan hydrochlo | 5MG
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Naluzotan hydrochlo | 5MG
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Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | 259.73 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fadrozole hydrochloride | 102676-31-3 | 99.9% | 259.73 | 10 MG
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Medchemexpress LLC VU6036720 hydrochloride | 99.7% | 473.39 | 5 MG
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VU6036720 hydrochloride is a potent and specific in vitro inhibitor of Kir4.1/5.1. It can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM and can be used for the research of brain and kidney.
- Potent and specific in vitro inhibitor of Kir4.1/5.1.
- Inhibits Kir4.1/5.1 channels with an IC50 value of 0.24 μM.
- Useful for research pertaining to the brain.
- Useful for research pertaining to the kidney.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 50 MG
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Embramine hydrochloride is a monoethanolamine used as an antihistamine and anticholinergic.
- Antihistamine
- Anticholinergic
- For research use only
- Related to Histamine receptor research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 1 ML
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Defactinib hydrochloride is a small-molecule focal adhesion kinase (FAK) inhibitor that suppresses FAK Tyr397 phosphorylation in a time- and dose-dependent manner. It is supplied as the hydrochloride salt and is available as a 10 mM solution in DMSO (1 mL) or as solid samples for biochemical and cellular research.
- Inhibits FAK phosphorylation at Tyr397
- Supplied as hydrochloride salt for improved solubility
- Available as 10 mM solution in DMSO (1 mL) and as solid samples
- High purity suitable for research assays
- Useful for studies of cell migration, invasion, and signaling
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 500 MG
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Trazodone hydrochloride is a triazolopyridine derivative classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity. The compound exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits anti-depressant and anti-insomnious activities
- Antagonizes α1- and α2-adrenergic receptors and histamine H1 receptors
- Minimal anticholinergic effects
- Binds to 5-HT1A receptor
- Reduces expression of neuroinflammatory markers
- Increases mRNA expression of BDNF and CREB
- Demonstrates neuroprotective effects
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Medchemexpress LLC 4-thiazolecarboxamide, N-(2-aminoethyl)-5-(3-fluorophenyl)-, hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 | C12H13ClFN3OS | 10 MG
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Ro 41-1049 hydrochloride is the hydrochloride salt of a reversible, selective monoamine oxidase A (MAO-A) inhibitor supplied as a white to off-white solid for research use. The compound is intended for biochemical and pharmacological studies, including receptor binding and enzyme activity assays, and is provided with supporting analytical documentation.
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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 100 MG
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Dopexamine hydrochloride is a β2 adrenergic receptor agonist, intended for research use only. This dopamine analogue exhibits agonist activity at β2 and dopaminergic receptors, making it suitable for studies on inflammatory response and organ protection.
- Attenuates systemic inflammatory response
- Reduces tissue leukocyte infiltration
- Protects against organ injury
- Reduces systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress
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Medchemexpress LLC Eglumegad hydrochloride | 176199-48-7 | 99.63% | 221.64 | 5 MG
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Eglumegad hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist. It protects neurons from NMDA toxicity and has anxiolytic- and antipsychotic-like effects.
- Highly potent and selective group II (mGlu2/3) receptor agonist.
- Protects neurons from NMDA toxicity.
- Has anxiolytic-like effects.
- Has antipsychotic-like effects.
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Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 25 MG
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Embramine hydrochloride is a monoethanolamine that functions as an antihistamine and anticholinergic. It is intended for research use only.
- Functions as an antihistamine
- Functions as an anticholinergic
- Targets Histamine Receptor
- Involved in GPCR/G protein, immunology/inflammation, and neuronal signaling pathways
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Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 1 ML
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Ansofaxine hydrochloride (LY03005) is a triple reuptake inhibitor that targets serotonin, dopamine, and norepinephrine. It is intended for research use only.
- Inhibits serotonin reuptake (IC50: 723 nM)
- Inhibits dopamine reuptake (IC50: 491 nM)
- Inhibits norepinephrine reuptake (IC50: 763 nM)
- Purity of 99.44%
- Molecular weight of 417.97
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Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 25 MG
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GB111-NH2 hydrochloride is identified as a cysteine cathepsin inhibitor and is suitable for cancer studies. It is intended for research use only and is not sold to patients.
- Cysteine cathepsin inhibitor
- Can be used for cancer study
- Available in solid and solution forms
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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 1 ML
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Dopexamine hydrochloride is a β2 adrenergic receptor agonist and a dopamine analogue. It exhibits agonist activity at both β2 and dopaminergic receptors. This compound can attenuate systemic inflammatory responses, reduce tissue leukocyte infiltration, and protect against organ injury, even at doses that do not impact global hemodynamics or regional microvascular flow.
- Attenuates systemic inflammatory response.
- Reduces tissue leukocyte infiltration.
- Protects against organ injury.
- Maintains global hemodynamics and regional microvascular flow.
- Reduces systemic inflammatory response to endotoxin.
- Impacts cytokine release, endothelial adhesion molecules, and oxidative stress.
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Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | 50 MG
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Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor, demonstrating antineoplastic activity. It effectively inhibits the two most prevalent PIK3CA somatic mutations, H1047R and E545K, and suppresses Akt phosphorylation in cells. This compound has shown to inhibit the growth of osteosarcoma cell lines and induce cell cycle arrest in the G0/G1 phase.
- Potent, orally active, and selective PI3Kα inhibitor
- Exhibits antineoplastic activity
- Effectively inhibits PIK3CA somatic mutations H1047R and E545K
- Suppresses Akt phosphorylation in cells
- Inhibits cell growth of osteosarcoma cell lines
- Induces cell cycle arrest in G0/G1 phase
- Significantly reduces tumor volumes in vivo
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Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 25 MG
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CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 25 MG
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